In this work, we exploit cell dynamics using a novel CNN architecture which allows multi-scale spatio-temporal feature extraction. Specifically, a novel recurrent neural network (RNN) architecture is proposed based on the integration of a Convolutional Long Short Term Memory (ConvLSTM) network with the U-Net. The proposed ConvLSTM-UNet network is constructed as a dual-task network to enable training with weakly annotated data, in the form of approximate cell centers, termed markers, when the complete cells’ outlines are not available.
